মঙ্গলবার, ২২ জানুয়ারী, ২০১৩

eCommerce for Small Business | Select Factoring

A new survey has shown that more small businesses are trading online, showing how valuable the?internet?is becoming to improving the prospects of the country?s SMEs. From the 2,200 companies interviewed, a 42% increase in those selling products online. There was also a 36% increase in businesses exporting their products overseas via their ecommerce sites.

This is especially significant as exporting has been hailed by the government as a way for small businesses to boost their growth in the face of tough domestic markets. The internet has also been helping start up ventures ? there was a 32% increase in start ups who trade exclusively online. This shows how the internet is opening up new doors for trading for even the smallest businesses, levelling the playing field.

These figures come a year after the launch of a government scheme to encourage small businesses to export more overseas. With the high street being affected so heavily by online sales ? see HMV and Comet as the prime examples ? trading via the internet is becoming all important to a huge number of business sectors and is in parts starting to become the consumers? first choice.

This survey revealed that more businesses were trading online as it was cheaper due to lower overheads, and nearly 20% said it was easier to sell their products online. However, traditional sales remain the dominant money maker, with 39% saying they make 50% or more of their sales online.

Investing in ecommerce is one way for a small business to expand its reach into the market, and even to start trading internationally. If you need to boost growth and ensure you?re making the most of the sales opportunities available to you, then trading online could be a step in the right direction.

Source: http://www.selectfactoring.co.uk/ecommerce-for-small-business

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A Check on Physicals - NYTimes.com

?Go Beyond Your Father?s Annual Physical. Live Longer, Feel Better?

This sales pitch for the Princeton Longevity Center?s ?comprehensive exam? promises, for $5,300, to take ?your health beyond the annual physical.? But it is far from certain whether this all-day checkup, and others less inclusive, make a meaningful difference to health or merely provide reassurance to the worried well.

Among physicians, researchers and insurers, there is an ongoing debate as to whether regular checkups really reduce the chances of becoming seriously ill or dying of an illness that would have been treatable had it been detected sooner.

No one questions the importance of regular exams for well babies, children and pregnant women, and the protective value of specific exams, like a Pap smear for sexually active women and a colonoscopy for people over 50. But arguments against the annual physical for all adults have been fueled by a growing number of studies that failed to find a medical benefit.

Some experts note that when something seemingly abnormal is picked up during a routine exam, the result is psychological distress for the patient, further testing that may do more harm than good, and increased medical expenses.

?Part of the problem of looking for abnormalities in perfectly well people is that rather a lot of us have them,? Dr. Margaret McCartney, a Scottish physician, wrote in The Daily Mail, a British newspaper. ?Most of them won?t do us any harm.?

She cited the medical saga of Brian Mulroney, former prime minister of Canada. A CT scan performed as part of a checkup in 2005 revealed two small lumps in Mr. Mulroney?s lungs. Following surgery, he developed an inflamed pancreas, which landed him in intensive care. He spent six weeks in the hospital, then was readmitted a month later for removal of a cyst on his pancreas caused by the inflammation.

The lumps on his lungs, by the way, were benign. But what if, you may ask, Mr. Mulroney?s lumps had been cancer? Might not the discovery during a routine exam have saved his life?

Logic notwithstanding, the question of benefits versus risks from routine exams can be answered only by well-designed scientific research.

Defining the value of a routine checkup ? determining who should get one and how often ? is especially important now, because next year the Affordable Care Act will add some 30 million people to the roster of the medically insured, many of whom will be eligible for government-mandated preventive care through an annual exam.

Dr. Ateev Mehrotra of the University of Pittsburgh School of Medicine, who directed a study of annual physicals in 2007, reported that an estimated 44.4 million adults in the United States undergo preventive exams each year. He concluded that if every adult were to receive such an exam, the health care system would be saddled with 145 million more visits every year, consuming 41 percent of all the time primary care doctors spend with patients.

There is already a shortage of such doctors and not nearly enough other health professionals ? physician assistants and nurse practitioners ? to meet future needs. If you think the wait to see your doctor is too long now, you may want to stock up on some epic novels to keep you occupied in the waiting room in the future.

Few would challenge the axiom that an ounce of prevention is worth a pound of cure. Lacking incontrovertible evidence for the annual physical, this logic has long been used to justify it:

? If a thorough exam and conversation about your well-being alerts your doctor to a health problem that is best addressed sooner rather than later, isn?t that better than waiting until the problem becomes too troublesome to ignore?

? What if you have a potentially fatal ailment, like heart disease or cancer, that may otherwise be undetected until it is well advanced or incurable?

? And wouldn?t it help to uncover risk factors like elevated blood sugar or high cholesterol that could prevent an incipient ailment if they are reversed before causing irreparable damage?

Even if there is no direct medical benefit, many doctors say that having their patients visit once a year helps to maintain a meaningful relationship and alert doctors to changes in patients? lives that could affect health. It is also an opportunity to give patients needed immunizations and to remind them to get their eyes, teeth and skin checked.

But the long-sacrosanct recommendation that everyone should have an annual physical was challenged yet again recently by researchers at the Nordic Cochrane Center in Copenhagen.

The research team, led by Dr. Lasse T. Krogsboll, analyzed the findings of 14 scientifically designed clinical trials of routine checkups that followed participants for up to 22 years. The team found no benefit to the risk of death or serious illness among seemingly healthy people who had general checkups, compared with people who did not. Their findings were published in November in BMJ (formerly The British Medical Journal).

In introducing their analysis, the Danish team noted that routine exams consist of ?combinations of screening tests, few of which have been adequately studied in randomized trials.? Among possible harms from health checks, they listed ?overdiagnosis, overtreatment, distress or injury from invasive follow-up tests, distress due to false positive test results, false reassurance due to false negative test results, adverse psychosocial effects due to labeling, and difficulties with getting insurance.?

Furthermore, they wrote, ?general health checks are likely to be expensive and may result in lost opportunities to improve other areas of health care.?

In summarizing their results, the team said, ?We did not find an effect on total or cause-specific mortality from general health checks in adult populations unselected for risk factors or disease. For the causes of death most likely to be influenced by health checks, cardiovascular mortality and cancer mortality, there were no reductions either.?

What, then, should people do to monitor their health?

Whenever you see your doctor, for any reason, make sure your blood pressure is checked. If a year or more has elapsed since your last blood test, get a new one.

Keep immunizations up to date, and get the screening tests specifically recommended based on your age, gender and known risk factors, including your family and personal medical history.

And if you develop a symptom, like unexplained pain, shortness of breath, digestive problems, a lump, a skin lesion that doesn?t heal, or unusual fatigue or depression, consult your doctor without delay. Seek further help if the initial diagnosis and treatment fails to bring relief.

Source: http://well.blogs.nytimes.com/2013/01/21/a-check-on-physicals/

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7 Free Android Apps for Easy Meal Planning : Best Free Tools and ...

Cooking apps provide more than a list of a few recipes. Many of these free Android apps provide instant grocery lists, easy menu planning programs, and helpful meal-choosing devices. Some can even pick a recipe for you based on the ingredients you have on hand.

Here are seven of the most fun and useful cooking apps available.

ChefTap allows you to import recipes from any site on the web so that you can keep your own virtual recipe box. From small blogs to corporate websites, ChefTap saves your favorite dishes along with links to the original posts.

Import entire recipe boxes that you?ve saved on sites like Epicurious or Allrecipes onto ChefTap. This app allows you to set up your own categories and sort recipes according to your personalized system.

Are you wondering what to cook tonight with the ingredients you have in the fridge? Allthecooks.com lets you scan through 150,000 recipes and helps you pick one as you say the ingredients you want to use.

Upload your own recipe photos to see what other users think. You can even ask a cooking question and get your answer in minutes.

If you want to eat healthier and get out of the habit of using processed foods, this free Android app is for you. With Allthecooks.com, it?s quick and easy to find nutritious recipes using real food ingredients that you?ll love.

Epicurious gives you step-by-step instructions for professional recipes. It also provides you with shopping lists for your favorites, allowing you to check off items as you go along.

The Epicurious app offers over 30,000 food and drink recipes. You can search for individual recipes or browse by theme or skill level. This app also offers a way for you to save your favorites and share them with your friends.

With the Allrecipes.com free Android app, you can search for your next dinner among the site?s 40,000 recipes. Look up specific recipes using dietary filters, like vegetarian or low-carb, or leave it up to chance with the dinner spinner.

Allrecipes allows you to search for?or scan?a particular item to find a useful recipe. Once you choose a recipe, it generates a handy shopping list containing all of the necessary ingredients.

BigOven?s impressive listing of over 250,000 recipes promises easy meal planning on the go. Look up popular recipe collections, read reviews, and search for meals by ingredient. BigOven also makes it easy to share complete menus by email, Facebook, Twitter, or Pinterest.

With BigOven?s simple drag-and-drop menu planning program, you can easily mark your calendar for future meals, then add them directly to your grocery list. You can even add your own recipes without typing by using RecipeScan, which is as simple as taking a picture.

Bacon lovers, rejoice! Here?s an app that?s made just for you.

Baconnection contains hundreds of recipes from bacon wrapped appetizers to bacon and chocolate desserts. It also entertains you with bacon-themed games, including Bacon Bits Trivia, which challenges your knowledge of this beloved meat.

Easy Chef Recipes contains 15,000 recipes. It has a built-in function that helps you decide what to make for dinner: simply give your phone a shake and Easy Chef Recipes will choose a meal for you.

Finding the perfect recipe for tonight?s dinner can be a challenge when you?re uninspired and short on time. Use these free Android apps to make meal planning fun, efficient, and mouthwatering.

The range of apps available now is incredible although it is important to compare mobile phones before purchase to make sure that your phone is able to access the apps listed above.

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About The Author

Tom is the tool geek. Let us know if you have a cool tool to share!

Source: http://dofollownet.com/7-free-android-apps-for-easy-meal-planning/

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সোমবার, ২১ জানুয়ারী, ২০১৩

One form of neuron turned into another in brain

Jan. 20, 2013 ? A new finding by Harvard stem cell biologists turns one of the basics of neurobiology on its head -- demonstrating that it is possible to turn one type of already differentiated neuron into another within the brain.

The discovery by Paola Arlotta and Caroline Rouaux "tells you that maybe the brain is not as immutable as we always thought, because at least during an early window of time one can reprogram the identity of one neuronal class into another," said Arlotta, an Associate Professor in Harvard's Department of Stem Cell and Regenerative Biology (SCRB).

The principle of direct lineage reprogramming of differentiated cells within the body was first proven by SCRB co-chair and Harvard Stem Cell Institute (HSCI) co-director Doug Melton and colleagues five years ago, when they reprogrammed exocrine pancreatic cells directly into insulin producing beta cells.

Arlotta and Rouaux now have proven that neurons too can change their mind. The work is being published on-line Jan. 20 by the journal Nature Cell Biology.

In their experiments, Arlotta targeted callosal projection neurons, which connect the two hemispheres of the brain, and turned them into neurons similar to corticospinal motor neurons, one of two populations of neurons destroyed in Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig's disease. To achieve such reprogramming of neuronal identity, the researchers used a transcription factor called Fezf2, which long as been known for playing a central role in the development of corticospinal neurons in the embryo.

What makes the finding even more significant is that the work was done in the brains of living mice, rather than in collections of cells in laboratory dishes. The mice were young, so researchers still do not know if neuronal reprogramming will be possible in older laboratory animals -- and humans. If it is possible, this has enormous implications for the treatment of neurodegenerative diseases.

"Neurodegenerative diseases typically effect a specific population of neurons, leaving many others untouched. For example, in ALS it is corticospinal motor neurons in the brain and motor neurons in the spinal cord, among the many neurons of the nervous system, that selectively die," Arlotta said. "What if one could take neurons that are spared in a given disease and turn them directly into the neurons that die off? In ALS, if you could generate even a small percentage of corticospinal motor neurons, it would likely be sufficient to recover basic functioning," she said.

The experiments that led to the new finding began five years ago, when "we wondered: in nature you never seen a neuron change identity; are we just not seeing it, or is this the reality? Can we take one type of neuron and turn it into another?" Arlotta and Rouaux asked themselves.

Over the course of the five years, the researchers analyzed "thousands and thousands of neurons, looking for many molecular markers as well as new connectivity that would indicate that reprogramming was occurring," Arlotta said. "We could have had this two years ago, but while this was a conceptually very simple set of experiments, it was technically difficult. The work was meant to test important dogmas on the irreversible nature of neurons in vivo. We had to prove, without a shadow of a doubt, that this was happening."

The work in Arlotta's lab is focused on the cerebral cortex, but "it opens the door to reprogramming in other areas of the central nervous system," she said.

Arlotta, an HSCI principal faculty member, is now working with colleague Takao Hensch, of Harvard's Department of Molecular and Cellular Biology, to explicate the physiology of the reprogrammed neurons, and learn how they communicate within pre-existing neuronal networks.

"My hope is that this will facilitate work in a new field of neurobiology that explores the boundaries and power of neuronal reprogramming to re-engineer circuits relevant to disease," said Paola Arlotta.

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Story Source:

The above story is reprinted from materials provided by Harvard University, via EurekAlert!, a service of AAAS.

Note: Materials may be edited for content and length. For further information, please contact the source cited above.


Journal Reference:

  1. Caroline Rouaux, Paola Arlotta. Direct lineage reprogramming of post-mitotic callosal neurons into corticofugal neurons in vivo. Nature Cell Biology, 2013; DOI: 10.1038/ncb2660

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/KplyB3QjEsc/130120150031.htm

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Factbox: Timeline for Obama inauguration events

(Reuters) - President Barack Obama will hold his public inauguration ceremony on Monday at the U.S. Capitol, followed by a parade to the White House.

Here is a guide to the main inauguration events. All times are Eastern Time.

9.a.m.

Former presidents, House of Representatives members, senators, governors and Cabinet designees begin to arrive at the U.S. Capitol for the public, ceremonial inauguration of President Obama and Vice President Biden.

9:30 a.m.

Fifth-grade chorus from Public School 22 in Staten Island, New York performs

10 a.m.

U.S. Marine Band performs

11:14 a.m.

First lady Michelle Obama takes her seat

11:18 a.m.

Vice President Joe Biden takes his seat

11:20 a.m.

President Barack Obama takes his seat

11:35 a.m.

Myrlie Evers-Williams, widow of slain civil-rights leader Medgar Evers, gives the invocation

11:38 a.m.

The Brooklyn (New York) Tabernacle Choir sings "The Battle Hymn of the Republic"

11:46 a.m.

Supreme Court Justice Sonia Sotomayor administers the vice presidential oath of office to Vice President Biden

11:50 a.m.

Singer James Taylor performs "America the Beautiful"

11:55 a.m.

U.S. Chief Justice John Roberts administers the presidential oath of office to President Obama

11:56 a.m.

Trumpets perform "Ruffles and Flourishes" and the U.S. Marine Band performs "Hail to the Chief," followed by a 21-gun salute

12 p.m.

Obama delivers the inaugural address

12:21 p.m.

Singer Kelly Clarkson performs "America (My Country 'Tis of Thee)"

12:26 p.m.

Cuban-American poet Richard Blanco reads a poem

12:30 p.m.

Benediction is delivered by the Rev. Luis Leon

12:34 p.m.

Singer Beyonce sings the national anthem, "The Star-Spangled Banner"

12:39 p.m.

President Obama signs official documents. The Obamas then attend the inauguration luncheon at the Capitol with the Bidens

2:32 p.m.

Review of the troops

2:36 p.m.

The Obamas and Bidens begin the inaugural parade down Pennsylvania Avenue to the White House

6 p.m.

Commander-in-chief's inaugural ball at the Washington Convention Center with military personnel and their spouses. The Obamas and Bidens are scheduled to attend.

6:30 p.m.

Official Inaugural Ball, at the Washington Convention Center. The Obamas and Bidens are scheduled to attend.

TUESDAY, JANUARY 22

10:30

National Prayer Service at the Washington National Cathedral attended by President Barack Obama and Vice President Joe Biden

(Reporting by Alistair Bell; Editing by Cynthia Osterman)

Source: http://news.yahoo.com/factbox-timeline-obama-inauguration-events-060149954.html

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George Heymont: All Hands On Deck!

This month, the media has been peppered with stories marking the one-year anniversary of the Costa Concordia disaster. While many people were quick to compare the ship's late-night collision with the sinking of the RMS Titanic, maritime historians were painfully aware of another, somewhat more eerie comparison that deserves mention.

Unlike the sinking of the Titanic (which was not a cruise ship), the Costa Concordia tragedy took place close to land, with the ship's waterlogged hull coming to rest at Isola de Grigio. While many people associate Long Beach Island, New Jersey with the devastation recently caused by Hurricane Sandy, early in the morning of September 8, 1934, the cruise ship S.S. Morro Castle was about eight miles off Long Beach Island when a fire broke out in a storage locker that eventually engulfed the entire ship in flames. The burning hulk eventually drifted ashore near the Asbury Park Convention Hall.


What does the Morro Castle tragedy have to do with the history of the American musical theatre? More than most people know. At the time, Cole Porter was working with Guy Bolton and P.G. Wodehouse on a new musical. Producer Vinton Freedley's original idea had involved a cruise ship and a bomb plot, followed by a shipwreck that left people stranded on a desert island.

After the Morro Castle disaster resulted in 138 deaths, Freedley turned to his director, Howard Lindsay, and brought in a publicist named Russel Crouse for a speedy rewrite (Lindsay and Crouse developed a reputation as Broadway show doctors and went on to write the scripts for Life With Father, Red, Hot and Blue, Call Me Madam, The Sound of Music, and Irving Berlin's last musical, Mr. President).

With its new script, Anything Goes had its Broadway premiere at the Alvin Theater on November 21, 1934 (10 weeks after the Morro Castle fire). Ethel Merman turned the title song as well as "I Get A Kick Out of You," "You're The Top," and "Blow, Gabriel, Blow" into popular hits. The 1962 off-Broadway revival starring Eileen Rodgers added "Friendship" from Porter's DuBarry Was A Lady (1939), as well as "It's De-Lovely" and "Goodbye, Little Dream, Goodbye" from Red, Hot, and Blue (1936).

The Wikipedia entry for Anything Goes details how songs were reassigned to different characters and/or interpolated from Porter's other musicals in a manner that would make Rossini proud. Timothy Crouse (Russel's son) and John Weidman updated the book for the 1987 Lincoln Center revival (starring Patti LuPone) and added songs from Red, Hot and Blue.


The national tour of the Roundabout Theatre Company's highly-acclaimed 2011 Broadway production roared into San Francisco's Golden Gate Theatre with a cast headed by Rachel York and Erich Bergen (Bergen will also perform his cabaret act on Monday, January 28 at Live at the Razz ).


As someone whose apartment includes a room with nearly 300 postcards, photos, and pictures of historic ocean liners covering the walls, I was thrilled to walk into the theatre and feast my eyes on Derek McLane's show curtain, which features a delicious three-stacker (the S. S. American) resembling the legendary Art Deco palace, S.S. Normandie. Coupled with Martin Pakledinaz's snazzy period costumes, McLane's sets keep the production on a constant high note.

2013-01-15-bergenyork.jpg
Erich Bergen and Rachel York in Anything Goes
Photo by: Joan Marcus


I tip my hat to Kathleen Marshall, who directed and choreographed this revival with the intention of adding plenty of snap, crackle, and pop to a show that is nearly 80 years old. The result is quite astounding: Not only do Porter's songs retain their freshness and lyrical appeal, the revised book from the 1987 production is a comic delight (those who have grown up in the era of jet travel have no idea how important celebrity spotting was to the transatlantic liner trade during the early 20th century).

2013-01-15-carmenmirandaatsea.jpg
Carmen Miranda posing at sea


Rachel York is a sleek and sultry Reno Sweeney who, in addition to being an enchanting belter, taps up a storm. As Billy Crocker, Erich Bergen scores strongly in a series of ridiculous costume gags while doing a great job as a romantic comedy lead. Others offering sturdy support include Dennis Kelly as Crocker's CEO boss, Elisha Whitney; Fred Applegate as gangster Moonface Martin; and Joyce Chittick as Erma (the gangster moll eager to give any sailor a helping hand).

2013-01-15-applegateyork.jpg
Fred Applegate and Rachel York in Anything Goes
Photo by: Joan Marcus


Sandra Shipley made the most out of her moments as Evangeline Harcourt, with Alex Finke taking a more lyrical approach to the role of her debutante daughter, Hope Harcourt. Special kudos to Edward Staudenmayer, whose Lord Evelyn Oakleigh brought down the house with his over-the-top Act II rendition of "The Gypsy In Me" (a song sung by Hope Harcourt in the original Broadway production).

Perhaps the biggest delight of the evening was to sit back and enjoy an energetic, entertaining musical which contains eight numbers that have become standards of the great American song book. If the audience's thunderous approval of Anything Goes was any indication, they just don't make shows like that anymore. Here's Sutton Foster performing the show's title song with the New York company at the 2011 Tony Awards.


To read more of George Heymont go to My Cultural Landscape

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Follow George Heymont on Twitter: www.twitter.com/geoheymont

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Source: http://www.huffingtonpost.com/george-heymont/all-hands-on-deck_b_2513731.html

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If you can afford private education but remain in the state

Thought I repost the OP although the debate has moved on a little .
It's going to be hard to avoid this becoming another state v private thread, but what I'm interested in is a slightly different take on that debate. It's not "which is better?" but "if you think state school is better even though you could afford private education, then why is that?"

The question is based on the assumptions that the DC in question is/are reasonably bright (so might benefit academically from academically selective education), that the state school is non-selective (as most people don't have access to grammar schools), and that you hope for your DC to go to a good university (to make the ????? fees worthwhile!)

I've been mulling this over ever since I heard some maths professor from Cambridge talking on the radio about the age-old private v state inequality of Oxbridge admissions. He was all for improving access for state school applicants but said that the simple fact was that for maths, even the best state schools generally teach only to the A-level syllabus, whereas the best private schools take their maths/further maths A-level candidates well beyond the syllabus and so the state school applicants are at a huge disadvantage - they simply don't have the starting level of knowledge required for the course.

This made me wonder: with this sort of unequal playing field, if you have the choice of private education, what reasons might you have not to take it?

Would be interested to hear from those who've made this choice - how it's working out, or if your DC have finished school now, how did it work out? Did they go to good universities/get good jobs, etc? On the other side of things, if you paid for private schooling but now regret it, why?

My DC go to a state school by the way.

Source: http://feedproxy.google.com/~r/RolePlayGateway/~3/7e74ZWqlrec/viewtopic.php

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